The ONE Business Case is a key tool to assist HEI’s and EU project managers with the digital transformation of their work. The timing of the resource is apt. The 2022 Erasmus+ Programme Guide stipulates that “projects should be designed in an eco-friendly way and should incorporate green practices in all its facets” and that participants should “come up with alternative, greener ways of implementing project activities.” The ONE Meeting Project seeks to make EU collaborations smarter, greener and more sustainable in the future.